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5-Benzylidene-3-ethyl rhodanine

CAS No. 18331-34-5

5-Benzylidene-3-ethyl rhodanine( —— )

Catalog No. M20405 CAS No. 18331-34-5

5-Benzylidene-3-ethyl rhodanine(BTR-1) is an active anti-cancer agent. BTR-1 activates apoptosis and induces cell death.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    5-Benzylidene-3-ethyl rhodanine
  • Note
    Research use only, not for human use.
  • Brief Description
    5-Benzylidene-3-ethyl rhodanine(BTR-1) is an active anti-cancer agent. BTR-1 activates apoptosis and induces cell death.
  • Description
    5-Benzylidene-3-ethyl rhodanine(BTR-1) is an active anti-cancer agent. BTR-1 activates apoptosis and induces cell death.
  • In Vitro
    BTR-1 (10, 50, 100, and 250 μM, 5 days) dose-dependently causes cytotoxicity in human leukemic cells, with IC50s of 8 and 6 μM at 48 and 72 h, respectively.Cell Viability AssayCell Line:T-cell leukemic cell lines Concentration:10, 50, 100, and 250 μM Incubation Time:5 days Result:Induced cytotoxicity in human leukemic cells in a dose-dependent manner.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    Apoptosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    18331-34-5
  • Formula Weight
    249.35
  • Molecular Formula
    C12H11NOS2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:25 mg/mL (100.26 mM)
  • SMILES
    CCN1C(=S)S\C(C1=O)=C/c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Moorthy B T Ravi S Srivastava M et al. Novel rhodanine derivatives induce growth inhibition followed by apoptosis[J]. Bioorganic and Medicinal Chemistry Letters 2010 20(21):6297-6301.
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